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Search Results to Timothy Ashby

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One or more keywords matched the following items that are connected to Ashby, Timothy

Item TypeName
Concept Multiple Myeloma
Academic Article Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma.
Academic Article The level of deletion 17p and bi-allelic inactivation of TP53 has a significant impact on clinical outcome in multiple myeloma.
Academic Article Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing.
Academic Article Loss of heterozygosity as a marker of homologous repair deficiency in multiple myeloma: a role for PARP inhibition?
Academic Article A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis.
Academic Article Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma.
Academic Article Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma.
Academic Article Clonal evolution in myeloma: the impact of maintenance lenalidomide and depth of response on the genetics and sub-clonal structure of relapsed disease in uniformly treated newly diagnosed patients.
Academic Article Poor overall survival in hyperhaploid multiple myeloma is defined by double-hit bi-allelic inactivation of TP53.
Academic Article Microhomology-mediated end joining drives complex rearrangements and overexpression of MYC and PVT1 in multiple myeloma.
Academic Article BRAF and DIS3 Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma.
Academic Article Differential RNA splicing as a potentially important driver mechanism in multiple myeloma.
Academic Article TarPan: an easily adaptable targeted sequencing panel viewer for research and clinical use.
Academic Article Accelerated single cell seeding in relapsed multiple myeloma.
Academic Article The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma.
Academic Article Monitoring treatment response and disease progression in myeloma with circulating cell-free DNA.
Academic Article Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma: A cohort study of patients in the Total Therapy clinical trials.
Academic Article Revealing the impact of structural variants in multiple myeloma.
Academic Article The molecular make up of smoldering myeloma highlights the evolutionary pathways leading to multiple myeloma.
Academic Article Author Correction: Accelerated single cell seeding in relapsed multiple myeloma.
Academic Article Chromothripsis as a pathogenic driver of multiple myeloma.
Academic Article TRIP13 modulates protein deubiquitination and accelerates tumor development and progression of B cell malignancies.
Academic Article Improving prognostic assignment in older adults with multiple myeloma using acquired genetic features, clonal hemopoiesis and telomere length.
Academic Article High-risk transcriptional profiles in multiple myeloma are an acquired feature that can occur in any subtype and more frequently with each subsequent relapse.
Academic Article Plasma cells expression from smouldering myeloma to myeloma reveals the importance of the PRC2 complex, cell cycle progression, and the divergent evolutionary pathways within the different molecular subgroups.
Academic Article Epigenetic Deregulation of Telomere-Related Genes in Newly Diagnosed Multiple Myeloma Patients.
Academic Article Notch3 signaling between myeloma cells and osteocytes in the tumor niche promotes tumor growth and bone destruction.
Academic Article Myeloma Genome Project Panel is a Comprehensive Targeted Genomics Panel for Molecular Profiling of Patients with Multiple Myeloma.
Academic Article Structural variants shape the genomic landscape and clinical outcome of multiple myeloma.
Academic Article CST6 suppresses osteolytic bone disease in multiple myeloma by blocking osteoclast differentiation.
Academic Article The spatio-temporal evolution of multiple myeloma from baseline to relapse-refractory states.
Academic Article Concomitant deletion of the short arm (del(1p13.3)) and amplification or gain (1q21) of chromosome 1 by fluorescence in situ hybridization are associated with a poor clinical outcome in multiple myeloma.
Academic Article A gene signature can predict risk of MGUS progressing to multiple myeloma.
Academic Article Expression of integrin ?-7 is epigenetically enhanced in multiple myeloma subgroups with high-risk cytogenetics.
Academic Article AKT supports the metabolic fitness of multiple myeloma cells by?restricting FOXO activity.
Academic Article High NEK2 expression in myeloid progenitors suppresses T?cell immunity in multiple myeloma.
Academic Article Pharmacologic targeting of the p62 ZZ domain enhances both anti-tumor and bone-anabolic effects of bortezomib in multiple myeloma.
Academic Article Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth.
Academic Article Prognostic value of ferritin in ASCT MM patients: integration with GEP models and ISS series systems.
Academic Article A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma.

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  • Multiple Myeloma